Louisville HC Jeff Brohm gives major update on star RB after suffering injury against Virginia Tech

Running back Isaac Brown left Louisville's game against Virginia Tech in the fourth quarter. The star running back suffered what appeared to be a non-contact injury during the scrimmage.

After the game, Louisville head coach Jeff Brohm provided an important update. According to WDRB's Eric Crawford, Brohm said:

“Isaac will be out for a while. We won't have him this game.”

Brohm essentially confirmed that Isaac Brown will miss his team's upcoming game against the California Golden Bears.

Golden bears The promising runner will now focus on getting back to fitness after Saturday's injury setback.

Brown has amassed a stat line of 91 carries, 782 rushing yards and five rushing TDs so far this season. He accumulated 130 rushing yards and a touchdown on 16 carries in the Virginia Tech victory. However, he is now set for a spell on the sidelines.

Jeff Brohm's Louisville vs. California

Jeff Brohm's Louisville Cardinals they have started the season with a record of 7-1. Their only loss this season came against the 24th-ranked Virginia Cavaliers. That loss was also the first in a conference game this season.

The following for the cardinals it's a home game against the California Golden Bears. They will have to navigate the matchup without their star running back, Isaac Brown, and that could mean the team relies more on its passing offense.

The Louisville Cardinals have been very impressive this season. Their statement win came against the Miami Hurricanes as they knocked the wind out of the Hurricanes playoff hopes. Now they will look to play spoiler for the rest of the season.

Here's what you need to know about Louisville's upcoming game against California

• Date: Saturday, November 8, 2025
• Live streaming: FuboTV and DAZN
• Time: 7:00 pm EST
• TV Channel: ACC Network or ESPN2
• Venue: L&N Stadium in Louisville, Ky